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2024
October 31, 2024: Visit AASLD booth 1147 for a free trial of HEPATIQ® - The Ultimate Liver Test™
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HEPATIQ provides a management option for the physician caring for a liver disease patient who tests abnormal on a blood test or elastography. The patient may in fact be healthier or sicker than the fibrosis measurements suggest (Hagström et al, Gastroenterology, Jan 2020; and Singh et al, Journal of Clinical Gastroenterology, Nov 2020). HEPATIQ may be used to assess liver functional reserve for such patients.
Furthermore, any patient needing treatment for liver cancer would benefit from an assessment of liver functional reserve prior to an intervention or surgery (D’Avola et al, Journal of Hepatology, 2022).
HEPATIQ provides six indices of liver disease from a single 20 minute SPECT scan: quantitative liver function, steatosis/steatohepatitis, portal hypertension, alcoholic hepatitis, fibrosis stage and variceal size.[1-27] HEPATIQ also calculates a physiologic stage of liver disease [28]: H0: Normal liver function, H1: Borderline liver function, H2: Steatotic cirrhosis likely, H3: Non-steatotic cirrhosis likely, H4: Liver decompensation likely, and H5: Liver transplant candidate. HEPATIQ is the only product on the market that precisely and non-invasively quantifies liver functional reserve. Other techniques such as biopsies, elastography and blood tests estimate liver fibrosis but do not quantify function. Research shows that function outperforms fibrosis in the prediction of outcomes. [5,7,12,13,16,17,21,22,24] Fibrosis measurements lack strong predictive power because liver disease outcomes are driven by the liver functional reserve, not the extent of fibrosis. The diseased liver compensates by generating new functioning lobules and instigating increased blood flow – a hemodynamic phenomenon missed by fibrosis measurements.[8]
The HEPATIQ indices are used for diagnosis, staging, interventions, and monitoring liver disease progression. They help identify those at risk of ascites, variceal bleeding, hepatic encephalopathy and liver-related death.[5,7] The numbers in square brackets are references to publications listed at www.hepatiq.com/publications/.
The HEPATIQ indices are used for diagnosis, staging, interventions, and monitoring liver disease progression. They help identify those at risk of ascites, variceal bleeding, hepatic encephalopathy and liver-related death.[5,7] The numbers in square brackets are references to publications listed at www.hepatiq.com/publications/.
September 2, 2024: Visit ASTRO booth 808 for the latest research on HEPATIQ
If you are attending the ASTRO conference in Washington DC, please visit our booth 808 to learn more about HEPATIQ® - The Ultimate Liver Test™.
A 2022 publication in the Journal of Hepatology, “The importance of liver functional reserve in the non-surgical treatment of hepatocellular carcinoma”, by D’Avola et al, states that “Patients with compensated cirrhosis and large liver functional reserve can always receive the most radical treatment”. However, “a more detailed and individualized assessment should be carried out in patients with poorer liver functional reserve”. The HEPATIQ test’s PHM and fLV indices provide a measure of the patient’s liver functional reserve. [7,11,13,14,15,18,19,20,22,24,28]
- HEPATIQ provides six indices of liver disease from a single 20 minute SPECT scan: quantitative liver function, steatosis/steatohepatitis, portal hypertension, alcoholic hepatitis, fibrosis stage and variceal size.[1-27] HEPATIQ also calculates a physiologic stage of liver disease [28]: H0: Normal liver function, H1: Borderline liver function, H2: Steatotic cirrhosis likely, H3: Non-steatotic cirrhosis likely, H4: Liver decompensation likely, and H5: Liver transplant candidate.
- HEPATIQ is the only product on the market that precisely and non-invasively quantifies liver functional reserve. Other techniques such as biopsies, elastography and blood tests estimate liver fibrosis but do not quantify function. Research shows that function outperforms fibrosis in the prediction of outcomes. [5,7,12,13,16,17,21,22,24] Fibrosis measurements lack strong predictive power because liver disease outcomes are driven by the liver functional reserve, not the extent of fibrosis. The diseased liver compensates by generating new functioning lobules and instigating increased blood flow – a hemodynamic phenomenon missed by fibrosis measurements.[8]
- The HEPATIQ indices are used for diagnosis, staging, interventions, and monitoring liver disease progression. They help identify those at risk of ascites, variceal bleeding, hepatic encephalopathy and liver-related death.[5,7] The numbers in square brackets are references to publications listed at www.hepatiq.com/publications/.